Dobrovoľníci pomáhajú s liekom na koronavírus, Folding@home dramaticky zvýšil výkon
Diskusia k článku: Dobrovoľníci pomáhajú s liekom na koronavírus, Folding@home dramaticky zvýšil výkon
Prispievajte do diskusií ako
prihlásený užívateľ.
Komentár, na ktorý odpovedáte:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The proximal origin of SARS-CoV-2
Od: asters
|
Pridané:
2020-03-22 15:41:42
While the analyses above suggest that SARS-CoV-2 may bind human ACE2 with high affinity, computational analyses predict that the interaction is not ideal7 and that the RBD sequence is different from those shown in SARS-CoV to be optimal for receptor binding7,11. Thus, the high-affinity binding of the SARS-CoV-2 spike protein to human ACE2 is most likely the result of natural selection on a human or human-like ACE2 that permits another optimal binding solution to arise. This is strong evidence that SARS-CoV-2 is not the product of purposeful manipulation.
https://go.nature.com/2QBI3c5
https://bit.ly/3dnXuyk
|